gene

PARD6A

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about PARD6A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for PARD6A — Partitioning Defect 6 Par-6 Family Cell Polarity Protein Alpha

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🧬 Gene Info

Gene Symbol	PARD6A
Full Name	Partitioning Defect 6 Par-6 Family Cell Polarity Protein Alpha
Chromosome	5q31.1
Protein Type	Scaffold Protein
Function	is a core component of the PAR3/PAR6/aPKC polarity complex that regulates cell polarity, asymmetric division, and synaptic function.
Molecular Weight	37 kDa
Amino Acids	345 aa
UniProt ID	Q9Y3D8
NCBI Gene ID	53600
Ensembl ID	ENSG00000102908
OMIM	607949
GeneCards	PARD6A
Human Protein Atlas	PARD6A
Cell polarity establishment	Asymmetric distribution of cellular components
Cytoskeletal organization	Actin and microtubule dynamics
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: PARD6A — AlphaFold Q9Y3D8 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

PARD6A — Partitioning Defect 6 Par-6 Family Cell Polarity Protein Alpha

gene · 747 words

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Pathway Diagram

graph TD
    PARD6A["PARD6A"]
    neurodegeneration["neurodegeneration"]
    PARD6A -->|"implicated_in"| neurodegeneration
    style PARD6A fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning PARD6A in their description or question text

No additional research found