PARP3

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolPARP3
Namepoly(ADP-ribose) polymerase family member 3
Typeprotein-coding
Sourcemygene

Summary

The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

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