PCBP2

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolPCBP2
Namepoly(rC) binding protein 2
Typeprotein-coding
Sourcemygene

Summary

The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf

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