Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PCDH19: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
PCDH19 - Protocadherin 19 linked to epilepsy and intellectual disability in females
| Gene Symbol | PCDH19 |
| Full Name | Protocadherin 19 |
| Chromosome | Xq21.3 |
| Protein Type | Cell adhesion molecule (cadherin superfamily) |
| Function | is a strong candidate for gene therapy approaches |
| Primary Expression | Brain (cortex, hippocampus, cerebellum), neural tissue |
| Amino Acids | 135 aa |
| Exons | 6 |
| UniProt ID | Q9UN68 |
| OMIM | 300460 |
| GeneCards | PCDH19 |
| Human Protein Atlas | PCDH19 |
| Genomic Coordinates | chrX:100,630,000-100,770,000 (GRCh38) |
| Gene Length | ~140 kb |
| Number of Exons | 6 coding exons |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
PCDH19["PCDH19"]
neurodegeneration["neurodegeneration"]
PCDH19 -->|"implicated_in"| neurodegeneration
style PCDH19 fill:#006494,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0
style neurodegeneration fill:#455a64,stroke:#333,stroke-width:1px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
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| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity