PDYN

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolPDYN
Nameprodynorphin
Typeprotein-coding
Sourcemygene

Summary

The protein encoded by this gene is a preproprotein that is proteolytically processed to form the secreted opioid peptides beta-neoendorphin, dynorphin, leu-enkephalin, rimorphin, and leumorphin. These peptides are ligands for the kappa-type of opioid receptor. Dynorphin is involved in modulating responses to several psychoactive substances, including cocaine. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010

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