PER3

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolPER3
Nameperiod circadian regulator 3
Typeprotein-coding
Sourcemygene

Summary

This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been link

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