PFKFB3

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolPFKFB3
Name6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Typeprotein-coding
Sourcemygene

Summary

The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and preven

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