PFKL

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolPFKL
Namephosphofructokinase, liver type
Typeprotein-coding
Sourcemygene

Summary

This gene encodes the liver (L) subunit of an enzyme that catalyzes the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate, which is a key step in glucose metabolism (glycolysis). This enzyme is a tetramer that may be composed of different subunits encoded by distinct genes in different tissues. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014].

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