PILRA

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolPILRA
Namepaired immunoglobin like type 2 receptor alpha
Typeprotein-coding
Sourcemygene

Summary

Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-

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