PIM1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolPIM1
NamePim-1 proto-oncogene, serine/threonine kinase
Typeprotein-coding
Sourcemygene

Summary

The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (wit

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