PLD3

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolPLD3
Namephospholipase D family member 3
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a member of the phospholipase D (PLD) family of enzymes that catalyze the hydrolysis of membrane phospholipids. The encoded protein is a single-pass type II membrane protein and contains two PLD phosphodiesterase domains. This protein influences processing of amyloid-beta precursor protein. Mutations in this gene are associated with Alzheimer disease risk. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Apr

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