Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PMS1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| CAG repeat expansion | causes (PMS1 drives somatic expansion of HTT CAG repeats t) | mechanism | 0.85 |
| Cag Repeat | stabilizes | mechanism | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| CRISPR | inhibits | mechanism | 0.80 |
| h-3e7d4f97 | targets | hypothesis | 0.65 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neurodegeneration | 2026-04-03 | 14 hypotheses Top: 0.622
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||