Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about POLB: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | POLB |
| Full Name | DNA Polymerase Beta |
| Chromosome | 8p12 |
| Protein Type | Enzyme |
| Function | DNA Polymerase Beta is essential for: |
| Primary Expression | all tissues |
| Molecular Weight | 39 kDa |
| Amino Acids | 335 aa |
| Exons | 14 |
| UniProt ID | P06746 |
| NCBI Gene ID | 5423 |
| Ensembl ID | ENSG00000067191 |
| OMIM | 174760 |
| GeneCards | POLB |
| Human Protein Atlas | POLB |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
POLB["POLB"]
neurodegeneration["neurodegeneration"]
POLB -->|"implicated_in"| neurodegeneration
style POLB fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning POLB in their description or question text
No additional research found