POLD4

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolPOLD4
NameDNA polymerase delta 4, accessory subunit
Typeprotein-coding
Sourcemygene

Summary

This gene encodes the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [p

This is an externally resolved entity

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