POLE

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolPOLE
NameDNA polymerase epsilon, catalytic subunit
Typeprotein-coding
Sourcemygene

Summary

This gene encodes the catalytic subunit of DNA polymerase epsilon. The enzyme is involved in DNA repair and chromosomal DNA replication. Mutations in this gene have been associated with colorectal cancer 12 and facial dysmorphism, immunodeficiency, livedo, and short stature. [provided by RefSeq, Sep 2013].

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