gene

POMT1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about POMT1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

0Connections

0Hypotheses

0Analyses

0Outgoing

0Incoming

0Experiments

0Debates

Summary

POMT1 (Protein O-Mannosyltransferase 1) - ER enzyme catalyzing O-mannosylation of alpha-dystroglycan, critical for muscle and brain development, implicated in Walker-Warburg syndrome and congenital muscular dystrophies

View on Wiki →

No AI portrait yet

🧬 Gene Info

Gene Symbol	POMT1
Full Name	Protein O-Mannosyltransferase 1
Chromosome	9q34.13
Protein Type	Glycosyltransferase (ER Membrane Protein)
Function	catalyzing O-mannosylation of alpha-dystroglycan; catalyzes O-mannosylation of α-dystroglycan
Subcellular Localization	the endoplasmic reticulum:
Molecular Weight	84 kDa
Amino Acids	750 aa
UniProt ID	Q9Y6A6
NCBI Gene ID	10585
GeneCards	POMT1
Human Protein Atlas	POMT1
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: POMT1 — AlphaFold Q9Y6A6 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

POMT1 — Protein O-Mannosyltransferase 1

gene · 2389 words

→

POMT1 Protein

protein · 1024 words

→

Pathway Diagram

graph TD
    POMT1["POMT1"]
    neurodegeneration["neurodegeneration"]
    POMT1 -->|"implicated_in"| neurodegeneration
    style POMT1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning POMT1 in their description or question text

No additional research found