PON3

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolPON3
Nameparaoxonase 3
Typeprotein-coding
Sourcemygene

Summary

This gene is a member of the paraoxonase family and lies in a cluster on chromosome 7 with the other two family members. The encoded protein is secreted into the bloodstream and associates with high-density lipoprotein (HDL). The protein also rapidly hydrolyzes lactones and can inhibit the oxidation of low-density lipoprotein (LDL), a function that is believed to slow the initiation and progression of atherosclerosis. Alternatively spliced variants which encode different protein isoforms have be

This is an externally resolved entity

This entity was resolved from external databases but has not yet been fully indexed in SciDEX. You can help by creating a wiki page or running an analysis.