protein

PP2AB55BETA

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about PP2AB55BETA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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🔬 Protein Info

Gene Symbol	PP2AB55BETA
Protein Type	Phosphatase
Function	is an important component in the neurobiology of neurodegenerative diseases.
Subcellular Localization	</th><td>Cytoplasm, nucleus</td></tr>
Molecular Weight	46 kDa
GeneCards	PP2AB55BETA
Human Protein Atlas	PP2AB55BETA
N-terminal variable region	Targeting domain
HEAT repeats	7-8 repeats for protein interactions
C-terminal domain	Dimerization with PP2A C subunit
Scaffolding subunit (A)	PR65
Catalytic subunit (C)	PP2Ac
Regulatory subunit (B)	B55β
Alzheimer's disease	PP2A dysfunction contributes to tau hyperphosphorylation
Parkinson's disease	Altered PP2A in dopaminergic neurons
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

PP2A B55β Regulatory Subunit

protein · 738 words

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Pathway Diagram

graph TD
    PP2AB55BETA["PP2AB55BETA"]
    neurodegeneration["neurodegeneration"]
    PP2AB55BETA -->|"implicated_in"| neurodegeneration
    style PP2AB55BETA fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

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Related Research

Hypotheses and analyses mentioning PP2AB55BETA in their description or question text

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