Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PPP1R9B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
PPP1R9B encodes spinophilin, a neuronal-specific phosphatase regulatory subunit critical for synaptic plasticity, dendritic spine morphology, and receptor signaling in neurodegenerative diseases.
| Gene Symbol | PPP1R9B |
| Full Name | Spinophilin |
| Chromosome | 17q21.33 |
| Function | regulatory subunit critical for synaptic plasticity |
| UniProt ID | [Q9Y2J8](https://www.uniprot.org/uniprot/Q9Y2J8) |
| Ensembl ID | ENSG00000127314 |
| GeneCards | PPP1R9B |
| Human Protein Atlas | PPP1R9B |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
PPP1R9B["PPP1R9B"]
neurodegeneration["neurodegeneration"]
PPP1R9B -->|"implicated_in"| neurodegeneration
style PPP1R9B fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||