gene

PPP2R1B

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PPP2R1B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Analyses

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0Experiments

Summary

ppp2r1b

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🧬 Gene Info

Gene Symbol	PPP2R1B
Full Name	Protein Phosphatase 2 Regulatory Subunit A Beta
Chromosome	11q23.2
Protein Family	HEAT repeat family
Function	is a sophisticated molecular machine composed of three distinct subunits that assemble to form a functional phosphatase complex.
Subcellular Localization	, and catalytic activity[@xing2006]. PPP2R1B provides essential structural scaffolding for PP2A holoenzyme assembly, and
UniProt ID	P30101
NCBI Gene ID	5519
Ensembl ID	ENSG00000137713
OMIM	616982
GeneCards	PPP2R1B
Human Protein Atlas	PPP2R1B
Encoded Protein	PP2A subunit A beta (PR65-beta)
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: PPP2R1B — AlphaFold P30101 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (6)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    PPP2R1B["PPP2R1B"]
    neurodegeneration["neurodegeneration"]
    PPP2R1B -->|"implicated_in"| neurodegeneration
    style PPP2R1B fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

PPP2R1B

Understanding Entity Pages

Summary

Wiki Pages (6)

PPP2R1B — Protein Phosphatase 2 Regulatory Subunit A Beta

PPP2CA — Protein Phosphatase 2 Catalytic Subunit Alpha

PP2A Protein (Protein Phosphatase 2A)

PP2A Protein

PP2A (PPP2R1A)