protein

PPT2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PPT2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for PPT2 Protein

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🔬 Protein Info

Gene Symbol	PPT2
Full Name	Palmitoyl-Protein Thioesterase 2
Chromosome	9p13.3
Protein Type	Enzyme
Function	The PPT2 gene encodes palmitoyl-protein thioesterase 2, a lysosomal enzyme that catalyzes the removal of palmitoyl (fatty acid) groups from modified proteins.
Primary Expression	most tissues with highest expression in:
Molecular Weight	32 kDa
Amino Acids	282 aa
UniProt ID	O60324
NCBI Gene ID	9378
Ensembl ID	ENSG00000141101
OMIM	614128
GeneCards	PPT2
Human Protein Atlas	PPT2
Inheritance Pattern	Autosomal recessive
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: PPT2 — AlphaFold O60324 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

PPT2 Gene

gene · 523 words

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PPT2 Protein

protein · 643 words

→

Pathway Diagram

graph TD
    PPT2["PPT2"]
    neurodegeneration["neurodegeneration"]
    PPT2 -->|"implicated_in"| neurodegeneration
    style PPT2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning PPT2 in their description or question text

No additional research found