protein

PRDX2PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PRDX2PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Analyses

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Summary

Prdx2 (Peroxiredoxin 2) is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.

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🔬 Protein Info

Gene Symbol	PRDX2PROTEIN
Protein Family	Peroxiredoxin family (typical 2-Cys)
Function	is an important component in the neurobiology of neurodegenerative diseases.
Primary Expression	erythrocytes and various tissues, including the brain
Molecular Weight	22 kDa (199 amino acids)
Amino Acids	199 aa
UniProt ID	P32189
GeneCards	PRDX2PROTEIN
Human Protein Atlas	PRDX2PROTEIN
N-terminal peroxidatic cysteine (Cys51)	the primary catalytic residue that reacts with H₂O₂
C-terminal resolving cysteine (Cys172)	forms a disulfide bond with the peroxidatic cysteine
Thioredoxin-like fold	conserved three-dimensional structure
Loop regions	contain the catalytic cysteines and determine substrate specificity
C-terminal extension	contributes to decamer formation
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: PRDX2PROTEIN — AlphaFold P32189 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

PRDX2 (Peroxiredoxin 2)

protein · 1431 words

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Pathway Diagram

graph TD
    PRDX2PROTEIN["PRDX2PROTEIN"]
    neurodegeneration["neurodegeneration"]
    PRDX2PROTEIN -->|"implicated_in"| neurodegeneration
    style PRDX2PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning PRDX2PROTEIN in their description or question text

No additional research found