protein

PRKRA

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PRKRA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for PRKRA Protein

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🔬 Protein Info

Gene Symbol	PRKRA
Full Name	Protein Activator of Interferon Induced Protein Kinase (PACT)
Chromosome	2q31.1
Function	PRKRA encodes the PACT (Protein Activator of PKR) protein, which functions as a co-activator for various protein kinases involved in stress responses and antiviral immunity.
Subcellular Localization	**: Cytoplasmic and nuclear
Molecular Weight	34.6 kDa
UniProt ID	Q9UBU2
NCBI Gene ID	55768
Ensembl ID	ENSG00000153159
OMIM	603415
GeneCards	PRKRA
Human Protein Atlas	PRKRA
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: PRKRA — AlphaFold Q9UBU2 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

PRKRA Gene

gene · 580 words

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PRKRA Protein

protein · 562 words

→

Pathway Diagram

graph TD
    PRKRA["PRKRA"]
    neurodegeneration["neurodegeneration"]
    PRKRA -->|"implicated_in"| neurodegeneration
    style PRKRA fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning PRKRA in their description or question text

No additional research found