Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PSD4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
PSD4 (Phosphatidylserine Decarboxylase 4) - enzyme involved in phospholipid metabolism and membrane composition in neurons
| Gene Symbol | PSD4 |
| Aliases | Phosphatidylserine Decarboxylase 4 |
| Chromosome | 5q31.2 |
| Protein Type | Enzyme |
| Function | encodes an enzyme involved in phospholipid metabolism, specifically catalyzing the conversion of phosphatidylserine (PS) to phosphatidylethanolamine (PE) through a unique decarboxylation reaction. |
| Molecular Weight | 46 kDa |
| Amino Acids | 417 aa |
| Exons | 14 |
| Ensembl ID | ENSG00000163520 |
| GeneCards | PSD4 |
| Human Protein Atlas | PSD4 |
| Human-Mouse | 88% identical at the amino acid level |
| Human-Zebrafish | 75% identical |
| Drosophila | Homolog with 62% identity |
| Yeast | PSD1 and PSD2 orthologs with 35-40% identity |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
PSD4["PSD4"]
neurodegeneration["neurodegeneration"]
PSD4 -->|"implicated_in"| neurodegeneration
style PSD4 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
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| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||