Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PSD93: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | DLG3 |
| Aliases | PSD93 |
| Chromosome | Xq13.1 |
| Protein Type | Kinase |
| Function | is a member of the membrane-associated guanylate kinase (MAGUK) family of scaffolding proteins. |
| Molecular Weight | 93 kDa |
| UniProt ID | Q92796 |
| NCBI Gene ID | 1749 |
| Ensembl ID | ENSG00000165646 |
| GeneCards | DLG3 |
| Human Protein Atlas | DLG3 |
| N-terminal region | Palmitoylation site for membrane targeting |
| SH3 domain | Binds to proline-rich motifs |
| Guanylate kinase (GK) domain | Catalytic domain with binding sites for GKAP/SAP90 |
| Dopaminergic synapse function | Role in maintaining dopaminergic synaptic architecture |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
PSD93["PSD93"]
neurodegeneration["neurodegeneration"]
PSD93 -->|"implicated_in"| neurodegeneration
style PSD93 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning PSD93 in their description or question text
No additional research found