protein

PTPRD

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PTPRD: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

2Connections

0Hypotheses

0Analyses

1Outgoing

1Incoming

Summary

Protein Tyrosine Phosphatase Receptor Type D (PTPRD): A large receptor-type phosphatase involved in synaptic plasticity, axon guidance, neuronal development, and implicated in Alzheimer's disease, cancer, and neuropsychiatric disorders

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🔬 Protein Info

Gene Symbol	PTPRD
Function	PTPRD is highly expressed in the nervous system, particularly in the cerebral cortex, hippocampus, cerebellum, and spinal cord.
Molecular Weight	220 kDa
Amino Acids	1917 aa
GeneCards	PTPRD
Human Protein Atlas	PTPRD
Interactions	PTPRF
KG Connections	2 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (3)

Knowledge base pages for this entity

Pathway Diagram

flowchart TD
    N0["PTPRD"]
    N1["PTPRF"]
    N0 -->|"co expressed with"| N1
    N1 -->|"inhibits"| N0

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    class N1 protein

Outgoing (1)

Target	Relation	Type	Str
PTPRF	co_expressed_with	protein	0.50

Incoming (1)

Source	Relation	Type	Str
PTPRF	inhibits	protein	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found