gene

PUNDC

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PUNDC: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

PUNDC1 Gene

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🧬 Gene Info

Gene Symbol	PUNDC1
Full Name	p53 and DNA Damage Responsive 1
Chromosome	13q14.11
Function	The PUNDC1 gene encodes p53 and DNA Damage Responsive 1, involved in DNA repair and genomic stability
UniProt ID	PUNDC1
NCBI Gene ID	90861
Ensembl ID	ENSG00000166148
OMIM	618511
GeneCards	PUNDC1
Human Protein Atlas	PUNDC1
DNA repair	Critical for maintaining genomic integrity
Cell cycle regulation	Coordinates DNA repair with cell cycle progression
[Apoptosis](/entities/apoptosis)	Modulates apoptotic response to DNA damage
Neuronal survival	Essential for long-term neuronal survival
R200C	functional studies
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: PUNDC — AlphaFold PUNDC1 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

PUNDC1 Gene

gene · 630 words

→

PUNDC1 Protein

protein · 549 words

→

Pathway Diagram

graph TD
    PUNDC["PUNDC"]
    neurodegeneration["neurodegeneration"]
    PUNDC -->|"implicated_in"| neurodegeneration
    style PUNDC fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning PUNDC in their description or question text

No additional research found