gene

QARS

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about QARS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for QARS — Glutaminyl-tRNA Synthetase

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🧬 Gene Info

Gene Symbol	QARS
Full Name	Glutaminyl-tRNA Synthetase
Chromosome	3p21.31
Protein Type	Synthetase
Function	encodes a member of the class I tRNA synthetase family that catalyzes the ATP-dependent attachment of L-glutamine to the 3' end of tRNA^Gln.
Primary Expression	both neurons and glia, with particular abundance in cerebellar Purkinje cells, hippocampal neurons, and cortical pyramidal neurons
Molecular Weight	64 kDa
Amino Acids	582 aa
Exons	26
UniProt ID	P47820
NCBI Gene ID	5859
Ensembl ID	ENSG00000172046
OMIM	613727
GeneCards	QARS
Human Protein Atlas	QARS
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: QARS — AlphaFold P47820 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

QARS — Glutaminyl-tRNA Synthetase

gene · 1981 words

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Pathway Diagram

graph TD
    QARS["QARS"]
    neurodegeneration["neurodegeneration"]
    QARS -->|"implicated_in"| neurodegeneration
    style QARS fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning QARS in their description or question text

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