Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about QPCT: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | QPCT |
| Full Name | Glutaminyl Cyclase |
| Aliases | QC, GCPII, GCPIII |
| Chromosome | 2p22.2 |
| Protein Type | Enzyme |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | various tissues, with high expression in the brain, particularly in regions vulnerable to neurodegeneration [4] |
| Molecular Weight | 38.5 kDa |
| Amino Acids | 360 aa |
| UniProt ID | Q96KH6 |
| Ensembl ID | ENSG00000125827 |
| GeneCards | QPCT |
| Human Protein Atlas | QPCT |
| Gene ID (NCBI) | 25788 |
| HGNC ID | 18329 |
| Associated Diseases | neurodegeneration |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
QPCT["QPCT"]
neurodegeneration["neurodegeneration"]
QPCT -->|"implicated_in"| neurodegeneration
style QPCT fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| ds-83b31ef18d49 | provides_data_for | dataset | 1.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| ds-83b31ef18d49 | data_in | dataset | 1.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity