RAC2

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolRAC2
NameRac family small GTPase 2
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a member of the Ras superfamily of small guanosine triphosphate (GTP)-metabolizing proteins. The encoded protein localizes to the plasma membrane, where it regulates diverse processes, such as secretion, phagocytosis, and cell polarization. Activity of this protein is also involved in the generation of reactive oxygen species. Mutations in this gene are associated with neutrophil immunodeficiency syndrome. There is a pseudogene for this gene on chromosome 6. [provided by RefSeq

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