RACGAP1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolRACGAP1
NameRac GTPase activating protein 1
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12. [provided by RefSeq, Feb 2016].

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