RAD50

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolRAD50
NameRAD50 double strand break repair protein
Typeprotein-coding
Sourcemygene

Summary

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination.

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This is an externally resolved entity

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