RAG2

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolRAG2
Namerecombination activating 2
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a protein that is involved in the initiation of V(D)J recombination during B and T cell development. This protein forms a complex with the product of the adjacent recombination activating gene 1, and this complex can form double-strand breaks by cleaving DNA at conserved recombination signal sequences. The recombination activating gene 1 component is thought to contain most of the catalytic activity, while the N-terminal of the recombination activating gene 2 component is thoug

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