Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RAMP3PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
The RAMP family consists of three related proteins (RAMP1, RAMP2, and RAMP3) that share a common structural architecture but confer distinct pharmacological properties when paired with CALCRL.
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| Gene Symbol | RAMP3PROTEIN |
| Chromosome | 7p13 |
| Function | is a small single-pass transmembrane protein that plays a crucial role in determining the pharmacology and function of certain G protein-coupled receptors (GPCRs). |
| Primary Expression | the nervous and cardiovascular systems - Pharmacology: Sensitive to CGRP receptor antagonists (e |
| Molecular Weight | 17 kDa |
| Amino Acids | 175 aa |
| Exons | 3 |
| GeneCards | RAMP3PROTEIN |
| Human Protein Atlas | RAMP3PROTEIN |
| Location | 7p13 |
| Gene size | ~4.5 kb |
| mRNA length | ~900 bp |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
RAMP3PROTEIN["RAMP3PROTEIN"]
neurodegeneration["neurodegeneration"]
RAMP3PROTEIN -->|"implicated_in"| neurodegeneration
style RAMP3PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning RAMP3PROTEIN in their description or question text
No additional research found