Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RARS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | RARS |
| Full Name | Arginyl-tRNA Synthetase |
| Chromosome | 5q31.3 |
| Protein Type | Enzyme |
| Function | is an essential enzyme encoded by the RARS gene that catalyzes the attachment of arginine to its cognate tRNA. |
| Pathways | mTOR, MAPK |
| NCBI Gene ID | 10684 |
| GeneCards | RARS |
| Human Protein Atlas | RARS |
| Amino acid sensing | RARS can function as a leucine sensor in the mTORC1 pathway [@leucine2014] |
| Signal transduction | Interacts with various signaling pathways including MAPK/ERK [@rarsa] |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtHPASTRING |
Knowledge base pages for this entity
graph TD
RARS["RARS"]
neurodegeneration["neurodegeneration"]
RARS -->|"implicated_in"| neurodegeneration
style RARS fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning RARS in their description or question text
No additional research found