Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RASA3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | RASA3 |
| Full Name | Ras GTPase-Activating Protein 3 |
| Chromosome | 13q34. |
| Function | ### Ras GAP Activity |
| Primary Expression | Brain, Platelets, Hematopoietic cells, Endothelium |
| Molecular Weight | 94 kDa |
| Amino Acids | 836 aa |
| Pathways | MAPK signaling |
| UniProt ID | Q9Y2T3 |
| NCBI Gene ID | 22821 |
| Ensembl ID | ENSG00000100739 |
| OMIM | 605424 |
| GeneCards | RASA3 |
| Human Protein Atlas | RASA3 |
| HRAS | Primary substrate with highest catalytic efficiency |
| Associated Diseases | Thrombocytopenia, Hemostatic disorders, Potential neurodegenerative implications |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
RASA3["RASA3"]
neurodegeneration["neurodegeneration"]
RASA3 -->|"implicated_in"| neurodegeneration
style RASA3 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning RASA3 in their description or question text
No additional research found