RASGRF1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolRASGRF1
NameRas protein specific guanine nucleotide releasing factor 1
Typeprotein-coding
Sourcemygene

Summary

The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathwa

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