VPS35

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolVPS35
NameVPS35 retromer complex component
Typeprotein-coding
Sourcemygene

Summary

This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serve

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