Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RGS14: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | RGS14 |
| Full Name | Regulator of G Protein Signaling 14 |
| Chromosome | 5q31.2 |
| Protein Type | Scaffold Protein |
| Primary Expression | layer 2/3 pyramidal neurons of the prefrontal and parietal cortex |
| Molecular Weight | 66 kDa |
| Amino Acids | 200 aa |
| Pathways | MAPK signaling, MAPK, MAPK pathway |
| UniProt ID | Q9YH5B4 |
| NCBI Gene ID | 10536 |
| Ensembl ID | ENSG00000172322 |
| OMIM | 607497 |
| GeneCards | RGS14 |
| Human Protein Atlas | RGS14 |
| Gαi/o | GoLoco binding |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
RGS14["RGS14"]
neurodegeneration["neurodegeneration"]
RGS14 -->|"implicated_in"| neurodegeneration
style RGS14 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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Multi-agent debates referencing this entity
No debates reference this entity