Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RGS7: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | RGS7 |
| Full Name | Regulator of G Protein Signaling 7 |
| Chromosome | 1p31.3 |
| Protein Type | Receptor |
| Function | RGS7 is a brain-specific RGS protein that forms complexes with Gβ5 (GNB5) to function as a GTPase-activating protein for Gαo. |
| Primary Expression | retina, olfactory bulb, cerebral cortex, and hippocampus |
| Molecular Weight | 56 kDa |
| Amino Acids | 120 aa |
| UniProt ID | Q96F10 |
| NCBI Gene ID | 2977 |
| Ensembl ID | ENSG00000182979 |
| OMIM | 602758 |
| GeneCards | RGS7 |
| Human Protein Atlas | RGS7 |
| Brain Region | Function |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
RGS7["RGS7"]
neurodegeneration["neurodegeneration"]
RGS7 -->|"implicated_in"| neurodegeneration
style RGS7 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||