gene

RGS8

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about RGS8: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for RGS8 — Regulator of G Protein Signaling 8

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🧬 Gene Info

Gene Symbol	RGS8
Full Name	Regulator of G Protein Signaling 8
Chromosome	1q23.3
Function	These G proteins mediate signaling from numerous neuronal receptors including dopamine receptors (particularly D2R), muscarinic acetylcholine receptors (M1/M4), serotonin receptors (5-HT1A/5-HT2), and
Primary Expression	Hippocampus, Cerebral cortex, Cerebellum, Striatum
Subcellular Localization	both presynaptic terminals and postsynaptic compartments. At presynaptic sites, RGS8 regulates neurotransmitter release
Amino Acids	210 aa
UniProt ID	P57774
NCBI Gene ID	8317
Ensembl ID	ENSG00000128564
OMIM	607231
GeneCards	RGS8
Human Protein Atlas	RGS8
Databases	GeneCards HPA STRING

🔮 Predicted Structure: RGS8 — AlphaFold P57774 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

RGS8 — Regulator of G Protein Signaling 8

gene · 633 words

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Pathway Diagram

graph TD
    RGS8["RGS8"]
    neurodegeneration["neurodegeneration"]
    RGS8 -->|"implicated_in"| neurodegeneration
    style RGS8 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning RGS8 in their description or question text

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