RIC3

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolRIC3
NameRIC3 acetylcholine receptor chaperone
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a member of the resistance to inhibitors of cholinesterase 3-like family which functions as a chaperone of specific 5-hydroxytryptamine type 3 receptor and nicotinic acetylcholine receptor subtypes. The encoded protein influences the folding and assembly of these receptor subunits in the endoplasmic reticulum and expression on the cell surface. This protein contains an N-terminal transmembrane domain, a proline-rich spacer, and a cytosolic C-terminal coiled-coil domain. Alterna

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