Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RIM1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | RIM1 |
| Full Name | Regulating Synaptic Membrane Exocytosis 1 |
| Chromosome | 6q13 (reported locus for human RIMS1) |
| Protein Type | Scaffold Protein |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | neuronal populations that demand fast and reliable transmission, including cortical and hippocampal glutamatergic neurons and cer |
| Molecular Weight | 175 kDa |
| NCBI Gene ID | RIMS1 Gene |
| Ensembl ID | ENSG00000067325 |
| GeneCards | RIM1 |
| Human Protein Atlas | RIM1 |
| Preferred symbol | RIMS1 (RIM1) |
| Full name | Regulating Synaptic Membrane Exocytosis 1 |
| Encoded protein | RIM1 Protein |
| Related pathway pages | Synaptic Vesicle Trafficking, Synaptic Dysfunction in Alzheimer's |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtHPASTRING |
Knowledge base pages for this entity
graph TD
RIM1["RIM1"]
neurodegeneration["neurodegeneration"]
RIM1 -->|"implicated_in"| neurodegeneration
style RIM1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||