gene

RIMS1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about RIMS1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Analyses

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Summary

Comprehensive information on RIMS1, a critical presynaptic active zone protein involved in neurotransmitter release, Alzheimer's disease, and Parkinson's disease.

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🧬 Gene Info

Gene Symbol	RIMS1
Full Name	Regulating Synaptic Membrane Exocytosis 1
Chromosome	6q13
Function	is a critical presynaptic active zone protein that orchestrates synaptic vesicle docking, priming, and calcium-triggered neurotransmitter release.
Molecular Weight	205 kDa
Amino Acids	770 aa
Exons	32
UniProt ID	Q86YW5
NCBI Gene ID	9747
Ensembl ID	ENSG00000165371
OMIM	606410
GeneCards	RIMS1
Human Protein Atlas	RIMS1
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: RIMS1 — AlphaFold Q86YW5 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

RIMS1 — Regulating Synaptic Membrane Exocytosis 1

gene · 1693 words

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RIMS1 Protein

protein · 671 words

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Pathway Diagram

graph TD
    RIMS1["RIMS1"]
    neurodegeneration["neurodegeneration"]
    RIMS1 -->|"implicated_in"| neurodegeneration
    style RIMS1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning RIMS1 in their description or question text

No additional research found