gene

RNC

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about RNC: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

RNC

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🧬 Gene Info

Gene Symbol	RNC
Full Name	RNA Binding Domain Containing
Chromosome	11p15.4
Function	is an essential protein in the microRNA (miRNA) biogenesis pathway.
Subcellular Localization	- Nucleus (primary processing site)
UniProt ID	[Q9Y5P5](https://www.uniprot.org/uniprot/Q9Y5P5)
Ensembl ID	ENSG00000132849
OMIM	612866
GeneCards	RNC
Human Protein Atlas	RNC
Pri-miRNA recognition	RNC binds to the stem-loop structure of pri-miRNAs via its double-stranded RNA binding domains (dsRBDs)
Drosha recruitment	RNC recruits and positions Drosha for accurate cleavage
Processing specificity	RNC determines which pri-miRNAs are processed
N-terminal region	Contains the Drosha-binding site
Central dsRBDs (2x)	Bind pri-miRNA hairpin structures
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

RNC

gene · 762 words

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Pathway Diagram

graph TD
    RNC["RNC"]
    neurodegeneration["neurodegeneration"]
    RNC -->|"implicated_in"| neurodegeneration
    style RNC fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning RNC in their description or question text

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