gene

RPL36A

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about RPL36A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Ribosomal Protein L36a (RPL36A)

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🧬 Gene Info

Gene Symbol	RPL36A
Chromosome	9q21.11
Function	RPL36A encodes a ribosomal protein that is a component of the 60S subunit.
Primary Expression	most tissues with high expression in brain
Ensembl ID	ENSG00000256039
GeneCards	RPL36A
Human Protein Atlas	RPL36A
60S Ribosomal Subunit	Larger eukaryotic ribosomal subunit containing RPL36A
28S rRNA	Primary ribosomal RNA component binding RPL36A
Integrated Stress Response (ISR)	eIF2α-ATF4 pathway activated during ribosomal dysfunction
Heat Shock Proteins (HSP70/HSP90)	Translation products
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Ribosomal Protein L36a (RPL36A)

gene · 667 words

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Pathway Diagram

graph TD
    RPL36A["RPL36A"]
    neurodegeneration["neurodegeneration"]
    RPL36A -->|"implicated_in"| neurodegeneration
    style RPL36A fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning RPL36A in their description or question text

No additional research found