Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RPL37: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | RPL37 |
| Function | encodes a ribosomal protein component of the 60S large ribosomal subunit. |
| Primary Expression | various brain regions - Highest expression in |
| Molecular Weight | 11 kDa |
| Amino Acids | 97 aa |
| Ensembl ID | ENSG00000145592 |
| GeneCards | RPL37 |
| Human Protein Atlas | RPL37 |
| Protein synthesis | Contributes to the catalytic center for peptide bond formation |
| Ribosome assembly | Essential for proper 60S subunit biogenesis |
| rRNA interaction | Interacts with 28S rRNA to stabilize the large subunit |
| Translation termination | Participates in the release factor binding site |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
RPL37["RPL37"]
neurodegeneration["neurodegeneration"]
RPL37 -->|"implicated_in"| neurodegeneration
style RPL37 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity