gene

RPL8

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about RPL8: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

RPL8 — Ribosomal Protein L8

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🧬 Gene Info

Gene Symbol	RPL8
Full Name	Ribosomal Protein L8
Aliases	L8, SA-1, RL8
Chromosome	8q24.3
Function	encodes a component of the large 60S ribosomal subunit.
Primary Expression	regions critical for learning and memory, including the hippocampus, cortex, and [cerebellum](/
Gene Type	Protein-coding
UniProt ID	P62917
NCBI Gene ID	6136
Ensembl ID	ENSG00000126267
GeneCards	RPL8
Human Protein Atlas	RPL8
Interactor	Function
RPL5	60S subunit assembly
RPL11	60S subunit assembly, ribosome biogenesis
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: RPL8 — AlphaFold P62917 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

RPL8 — Ribosomal Protein L8

gene · 1699 words

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Pathway Diagram

graph TD
    RPL8["RPL8"]
    neurodegeneration["neurodegeneration"]
    RPL8 -->|"implicated_in"| neurodegeneration
    style RPL8 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity