Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RPS11: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Comprehensive gene profile for RPS11 (Ribosomal Protein S11), a component of the 40S ribosomal subunit with critical roles in protein synthesis, neuronal function, and neurodegenerative disease.
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| Gene Symbol | RPS11 |
| Full Name | Ribosomal Protein S11 |
| Chromosome | 5p13.3 |
| Protein Family | Ribosomal protein S11 family |
| Function | The 40S subunit binds the 60S subunit to form the complete 80S ribosome during translation initiation. |
| Primary Expression | Ubiquitous; high in brain, liver, pancreas |
| Molecular Weight | 18.7 kDa |
| UniProt ID | P62280 |
| NCBI Gene ID | 6205 |
| Ensembl ID | ENSG00000198099 |
| OMIM | 603637 |
| GeneCards | RPS11 |
| Human Protein Atlas | RPS11 |
| α-helical domain | Predominant secondary structure |
| β-sheet element | Forms RNA-binding surface |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
RPS11["RPS11"]
neurodegeneration["neurodegeneration"]
RPS11 -->|"implicated_in"| neurodegeneration
style RPS11 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning RPS11 in their description or question text
No additional research found