Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RPS19: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
RPS19 (Ribosomal Protein S19) is a ribosomal protein component of the 40S ribosomal subunit. Mutations in RPS19 cause Diamond-Blackfan anemia and have been linked to neurological disorders. The protein is essential for ribosome biogenesis and protein s...
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| Gene Symbol | RPS19 |
| Aliases | Ribosomal Protein S19 |
| Chromosome | 19q13.2 |
| Protein Family | Ribosomal protein S19 family |
| Protein Type | Gene |
| Function | is a gene that encodes a component protein of the 40S ribosomal subunit. |
| Molecular Weight | 16 kDa |
| Amino Acids | 145 aa |
| Exons | 6 |
| NCBI Gene ID | 6201 |
| GeneCards | RPS19 |
| Human Protein Atlas | RPS19 |
| Genomic position | Approximately 42,500,000-42,520,000 (GRCh38) |
| Strand | Plus/-sense strand |
| Gene family | Ribosomal protein S19 family |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtHPASTRING |
Knowledge base pages for this entity
graph TD
RPS19["RPS19"]
neurodegeneration["neurodegeneration"]
RPS19 -->|"implicated in"| neurodegeneration
Ribosome_Biogenesis(["Ribosome Biogenesis"])
RPS19 -->|"regulates"| Ribosome_Biogenesis
style RPS19 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#fff
style Ribosome_Biogenesis fill:#2a2a1a,stroke:#ffd54f,stroke-width:1px,color:#ffd54f| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning RPS19 in their description or question text
No additional research found